Analytical Data
-
Gene name
GNAT2
- Application
-
Alternative Names
Transducin alpha-2 chain
-
Species
Bovine
-
Source
E. coli
-
Tag
N- His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P04696
-
Expression Region
2-354aa
-
Molecular Weight
44 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GNAT2, a crucial member of the guanine nucleotide-binding protein family, plays an essential role in phototransduction, the process by which light signals are converted into electrical signals in the retina. Mutations in the GNAT2 gene have been associated with various retinal diseases, including congenital stationary night blindness (CSNB) and other vision disorders, making it a significant target for research in ophthalmology and genetics. The study of GNAT2 recombinant proteins has garnered interest for understanding the molecular mechanisms underlying these conditions, as well as for the potential development of therapeutic strategies aimed at restoring normal visual function. By producing and characterizing GNAT2 recombinant proteins, researchers can elucidate its structure, function, and interactions within photoreceptor cells, paving the way for targeted interventions that may benefit individuals affected by GNAT2-related retinal diseases. Furthermore, the insights gained from GNAT2 research can contribute to the broader understanding of G protein-coupled signaling pathways, which are fundamental to many cellular processes. Thus, this research not only holds promise for addressing specific genetic disorders but also enhances our knowledge of fundamental biological mechanisms related to vision and cellular communication.
