Analytical Data
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Gene name
MATN3
- Application
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Alternative Names
AV009181; DIPOA; EDM5; HOA; MATN3; MATN3_HUMAN; Matrilin 3; Matrilin-3; OADIP; OS2
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Species
Human
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Source
E. coli
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Tag
N- His & C- Myc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O15232
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Expression Region
29-486aa
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Molecular Weight
57.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MATN3 (Matrilin-3) is a member of the matrilin protein family, which is crucial for the structural integrity of cartilage and other connective tissues. It plays an essential role in the assembly of extracellular matrix components, contributing to the biomechanical properties of articular cartilage. Research has shown that mutations in the MATN3 gene are associated with various musculoskeletal disorders, including osteoarthritis and skeletal dysplasias. Understanding the structure and function of MATN3 is vital for elucidating the pathogenic mechanisms underlying these conditions. Given its significance in cartilage biology, the recombinant production of MATN3 protein has gained attention for its potential applications in regenerative medicine and tissue engineering. By generating MATN3 in a controlled environment, researchers aim to study its interactions with other matrix proteins, assess its biomechanical properties, and explore its potential as a therapeutic target. Additionally, recombinant MATN3 can be used to develop biomaterials that mimic the extracellular matrix, providing a platform for investigating cartilage repair and regeneration strategies. Thus, ongoing research on MATN3 recombinant protein underscores its importance in both basic biology and clinical applications related to cartilage health and disease management.
