Analytical Data
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Gene name
RAC3
- Application
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Alternative Names
p21-Rac3
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P60763
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Expression Region
1-192aa
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Molecular Weight
48 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RAC3, a member of the Rho family of GTPases, has garnered significant attention in recent years due to its pivotal role in various cellular processes, including cell proliferation, migration, and differentiation. This protein is involved in the regulation of cytoskeletal dynamics and is implicated in signaling pathways that promote cancer progression. Dysregulation of RAC3 activity has been associated with several malignancies, making it a potential target for therapeutic intervention. Recent studies have focused on the structural characterization and functional analysis of RAC3, particularly through the use of recombinant protein techniques. By producing and purifying RAC3 as a recombinant protein, researchers aim to elucidate its molecular mechanisms and interactions with downstream effectors. This research is critical for understanding how RAC3 contributes to tumorigenesis and for identifying novel strategies to inhibit its aberrant signaling in cancer cells. Advanced techniques such as X-ray crystallography and cryo-electron microscopy are increasingly utilized to gain insights into the three-dimensional structure of RAC3 and its complexes, paving the way for structure-based drug design. Overall, the study of RAC3 recombinant proteins is fundamental for advancing our knowledge of cellular regulation and developing targeted therapies for cancer treatments.
