Analytical Data
-
Gene name
RAP2B
- Application
-
Alternative Names
MGC20484; RAP 2B; RAP2A; Rap2b; RAP2B member of RAS oncogene family; RAP2B_HUMAN; Ras family small GTP binding protein RAP2B; Ras related protein RAP 2B; Ras related protein RAP2B; Ras-related protein Rap-2b; Small GTP binding protein
-
Species
Human
-
Source
E. coli
-
Tag
N- GST
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P61225
-
Expression Region
1-183aa
-
Molecular Weight
47.2 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RAP2B (Ras-related protein 2B) is a member of the Ras superfamily of GTPases, which are crucial regulators of diverse cellular processes, including growth, differentiation, and vesicle trafficking. It has been implicated in various physiological functions and pathological conditions, such as cancer and cardiovascular diseases. The study of RAP2B, especially through the production of recombinant protein, allows researchers to investigate its structure-function relationships and interaction with effector proteins. Recombinant RAP2B can be used to elucidate the mechanisms by which it regulates cellular signaling pathways and its role in disease progression. Furthermore, the development of RAP2B as a therapeutic target requires an in-depth understanding of its biological functions, making the production and characterization of this protein vital for advancing molecular biology and potential therapeutic interventions. By utilizing techniques such as molecular cloning and protein expression systems, researchers can produce active RAP2B, thereby facilitating the study of its biochemical properties, interaction with other cellular proteins, and impact on various signaling cascades. This recombinant protein approach not only enhances our understanding of RAP2B's role in normal physiology but also its aberrations in disease states, contributing to the broader field of cancer research and targeted therapies.
