Analytical Data
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基因名
TAS2R38
- Application
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别名
TAS2R38；PTC；Taste receptor type 2 member 38
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P59533
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表达区间
1-333aa
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氨基酸序列
MLTLTRIRTVSYEVRSTFLFISVLEFAVGFLTNAFVFLVNFWDVVKRQALSNSDCVLLCL SISRLFLHGLLFLSAIQLTHFQKLSEPLNHSYQAIIMLWMIANQANLWLAACLSLLYCSK LIRFSHTFLICLASWVSRKISQMLLGIILCSCICTVLCVWCFFSRPHFTVTTVLFMNNNT RLNWQIKDLNLFYSFLFCYLWSVPPFLLFLVSSGMLTVSLGRHMRTMKVYTRNSRDPSLE AHIKALKSLVSFFCFFVISSCAAFISVPLLILWRDKIGVMVCVGIMAACPSGHAAILISG NAKLRRAVMTILLWAQSSLKVRADHKADSRTLC
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TAS2R38 is a member of the TAS2R family of bitter taste receptors, which play a crucial role in the perception of bitterness in various plant compounds and are linked to dietary preferences and nutritional choices. Variations in the TAS2R38 gene result in differential sensitivity to bitter compounds, leading to phenotypic differences in taste perception among individuals. This gene exhibits polymorphisms, particularly in populations of European descent, leading to distinct taste phenotypes: the "supertasters," who are highly sensitive to bitter flavors, and "non-tasters," who have a reduced ability to perceive bitterness. The study of TAS2R38 recombinant proteins is significant for understanding the molecular mechanisms behind bitter taste sensitivity and has implications for fields like nutrition, genetics, and public health. By expressing and characterizing TAS2R38 in a recombinant system, researchers can investigate the receptor's functional properties, ligand interactions, and signaling pathways. This research not only sheds light on basic taste biology but also informs strategies for developing food products that cater to different taste preferences, potentially influencing dietary habits and health outcomes. Understanding TAS2R38's role in taste perception may also contribute to insights on how genetic differences affect food choices and susceptibility to taste-related health conditions, highlighting the interplay between genetics and dietary behaviors.
