Analytical Data
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基因名
WNT1
- Application
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别名
WNT1；INT1；Proto-oncogene Wnt-1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P04628
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表达区间
28-370aa
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氨基酸序列
ANSSGRWWGI VNVASSTNLL TDSKSLQLVL EPSLQLLSRK QRRLIRQNPG ILHSVSGGLQ SAVRECKWQF RNRRWNCPTA PGPHLFGKIV NRGCRETAFI FAITSAGVTH SVARSCSEGS IESCTCDYRR RGPGGPDWHW GGCSDNIDFG RLFGREFVDS GEKGRDLRFL MNLHNNEAGR TTVFSEMRQE CKCHGMSGSC TVRTCWMRLP TLRAVGDVLR DRFDGASRVL YGNRGSNRAS RAELLRLEPE DPAHKPPSPH DLVYFEKSPN FCTYSGRLGT AGTAGRACNS SSPALDGCEL LCCGRGHRTR TQRVTERCNC TFHWCCHVSC RNCTHTRVLH ECL
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分子量
38 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
WNT1 is a member of the Wnt family of secreted glycoproteins that play crucial roles in various biological processes, including embryonic development, cell proliferation, and differentiation. It is particularly important in the regulation of stem cell maintenance and tissue homeostasis. Aberrations in WNT signaling pathways, including the dysregulation of WNT1, have been implicated in several diseases, such as cancers and neurodegenerative disorders. The study of recombinant WNT1 protein has garnered significant interest, as it provides insight into the molecular mechanisms underlying its function and facilitates the exploration of potential therapeutic applications. Recombinant WNT1 can be effectively produced using various expression systems, allowing researchers to study its biological properties and interactions with receptors and downstream signaling molecules. Understanding the role of WNT1 in cellular contexts is vital for elucidating its contributions to health and disease, and could pave the way for the development of targeted therapies that modulate WNT signaling pathways.
