Analytical Data
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基因名
WNT9B
- Application
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别名
WNT9B；WNT14B；WNT15；Protein Wnt-9b
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O14905
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表达区间
1-329aa
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氨基酸序列
MRPPPALALAGLCLLALPAAAASYFGLTGREVLTPFPGLGTAAAPAQGGA HLKQCDLLKLSRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRHERWNC SLEGRTGLLKRGFKETAFLYAVSSAALTHTLARACSAGRMERCTCDDSPG LESRQAWQWGVCGDNLKYSTKFLSNFLGSKRGNKDLRARADAHNTHVGIK AVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQVLKLRYDSAVKVSS ATNEALGRLELWAPARQGSLTKGLAPRSGDLVYMEDSPSFCRPSKYSPGT AGWSAVARSQLITTSTSRIQAILPSQLPE
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
WNT9B is a member of the Wnt family of secreted glycoproteins that play a crucial role in various biological processes, including embryonic development, cell differentiation, and stem cell maintenance. Its involvement in signaling pathways has garnered substantial interest due to its implications in cancer progression, as aberrant Wnt signaling can lead to tumorigenesis. Research has indicated that WNT9B is particularly important in the development of organs such as the kidney and the lungs, influencing cellular behaviors like proliferation, migration, and fate determination. Furthermore, studies have demonstrated that WNT9B signaling can modulate various physiological responses, making it a potential therapeutic target for conditions like renal diseases and certain cancers. The study of recombinant WNT9B proteins is essential for elucidating its biological functions and mechanisms of action, enabling researchers to explore its potential applications in regenerative medicine and targeted therapies. Utilizing recombinant technology to produce WNT9B proteins allows for a better understanding of its interactions with receptors and other molecular partners in the Wnt signaling pathway, paving the way for innovative approaches to manipulate these pathways for therapeutic benefit. Such advancements can lead to new strategies for diagnosing and treating diseases linked to WNT9B dysregulation, highlighting the significance of this protein in both basic research and clinical applications.
