Cat: PA1000-259DB

Recombinant Human ATF1 Protein,His

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Analytical Data

  • 基因名

    ATF1

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    ATF1;Cyclic AMP-dependent transcription factor ATF-1

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P39905

  • 表达区间

    78-211aa

  • 氨基酸序列

    SPDKQMAVLP RRERNRQAAA ANPENSRGKG RRGQRGKNRG CVLTAIHLNV TDLGLGYETK EELIFRYCSG SCDAAETTYD KILKNLSRNR RLVSDKVGQA CCRPIAFDDD LSFLDDNLVY HILRKHSAKR CGCI

  • 分子量

    15.1 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

ATF1 (Activating Transcription Factor 1) is a member of the basic leucine zipper (bZIP) family of transcription factors that plays a crucial role in various cellular processes, including stress responses, metabolism, and cell differentiation. It is particularly noted for its involvement in the regulation of genes associated with the cellular response to stressors such as oxidative stress, hypoxia, and inflammatory signals. Research into ATF1 has gained significant interest due to its potential implications in various diseases, including cancer, where its dysregulation may contribute to tumor progression and resistance to therapies. The recombinant expression of ATF1 protein allows for detailed studies of its functional properties, structural characteristics, and interaction with other cellular proteins. This is achieved through techniques such as molecular cloning and protein purification, which enable researchers to create and study the recombinant form of ATF1 in vitro. These studies are essential for understanding its mechanism of action and role in gene regulation, as well as for potential therapeutic applications targeting ATF1 pathways. Additionally, the investigation of ATF1 dynamics can provide insights into its role in pathophysiological states, ultimately contributing to the development of novel strategies for disease intervention. Overall, the study of recombinant ATF1 protein represents a promising avenue for advancing our knowledge of transcriptional regulation and its implications in health and disease.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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