Analytical Data
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Gene name
NOR1
- Application
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Alternative Names
NOR1；CHN；CSMF；MINOR；Nuclear receptor subfamily 4 group A member 3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O15162
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Expression Region
1-288aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MDKQNSQMNA SHPETNLPVG YPPQYPPTAF QGPPGYSGYP GPQVSYPPPP AGHSGPGPAG FPVPNQPVYN QPVYNQPVGA AGVPWMPAPQ PPLNCPPGLE YLSQIDQILI HQQIELLEVL TGFETNNKYE IKNSFGQRVY FAAEDTDCCT RNCCGPSRPF TLRIIDNMGQ EVITLERPLR CSSCCCPCCL QEIEIQAPPG VPIGYVIQTW HPCLPKFTIQ NEKREDVLKI SGPCVVCSCC GDVDFEIKSL DEQCVVGKIS KHWTGILREA FTDADNFGIQ FPLDLDVK
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Molecular Weight
34 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NOR1, a member of the nuclear receptor family, has garnered significant attention in recent years due to its pivotal role in regulating various physiological processes, including metabolism, differentiation, and cardiovascular function. Originally identified for its involvement in the signaling pathways of steroid hormones, NOR1 exhibits unique ligand specificity and is known to transcriptionally modulate target genes related to energy homeostasis and cellular stress responses. The intricate regulatory mechanisms by which NOR1 operates make it a promising candidate for therapeutic interventions in diseases such as obesity, diabetes, and cardiovascular disorders. Recent studies have elucidated its function as a key mediator of gene expression in response to metabolic cues, highlighting its importance in maintaining metabolic health. The recombinant expression of NOR1 provides a valuable tool for exploring its molecular interactions and regulatory pathways. Research focusing on the structure-function relationship of NOR1, particularly through the production of recombinant proteins, enables the investigation of its ligand-binding properties and transcriptional activities. By employing techniques such as crystallography and site-directed mutagenesis, scientists aim to decipher the functional domains of NOR1, which may lead to novel strategies for manipulating its activity in a therapeutic context. Thus, the study of NOR1 recombinant proteins not only advances our understanding of nuclear receptor biology but also holds potential for developing innovative treatments targeting metabolic and cardiovascular diseases.
