Analytical Data
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基因名
GALNT14
- Application
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别名
Polypeptide GalNAc transferase 14 ;GalNAc-T14 ;pp-GaNTase 14Protein-UDP acetylgalactosaminyltransferase 14UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14
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种属
Human
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96FL9
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表达区间
1-552aa
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分子量
80.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GALNT14, a member of the Golgi N-acetylgalactosaminyltransferase family, plays a crucial role in the initiation of O-glycosylation, a post-translational modification that significantly influences protein function, stability, and cell signaling. Alterations in GALNT14 expression and activity have been linked to various diseases, including cancer, where aberrant glycosylation patterns can contribute to tumor progression and metastasis. The study of GALNT14 recombinant proteins is essential for understanding its enzymatic properties and substrate specificity, which can elucidate its biological functions and the pathways it regulates. By generating recombinant GALNT14, researchers can investigate its role in glycosylation processes and how it interacts with different substrates. Furthermore, the development of monoclonal antibodies against GALNT14 can be valuable for clinical diagnostics and therapeutic applications. Ongoing research aims to explore the potential of targeting GALNT14 for cancer treatment and to unravel the complex mechanisms by which it influences cellular behavior, ultimately contributing to the development of novel therapeutic strategies in oncology and beyond.
