Cat: PA1000-646DB

Recombinant Human CLMP Protein,His

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Analytical Data

  • Gene name

    CLMP

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    CLMP;ACAM;ASAM;CXADR-like membrane Protein

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9H6B4

  • Expression Region

    19-233aa

  • AA Sequence

    THTEIKRVAEEKVTLPCHHQLGLPEKDTLDIEWLLTDNEGNQKVVITYSS RHVYNNLTEEQKGRVAFASNFLAGDASLQIEPLKPSDEGRYTCKVKNSGR YVWSHVILKVLVRPSKPKCELEGELTEGSDLTLQCESSSGTEPIVYYWQR IREKEGEDERLPPKSRIDYNHPGRVLLQNLTMSYSGLYQCTAGNEAGKES CVVRVTVQYVQSIGMVDHHHHHH

  • Molecular Weight

    25 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

CLMP (Carcinoembryonic Antigen-related Cell Adhesion Molecule 1) is a member of the CEACAM family, known for its role in cell adhesion and communication. Recent studies have indicated that CLMP plays a critical role in various biological processes, including embryonic development, immune responses, and tumor progression. The understanding of CLMP's function has gained particular interest due to its potential implications in cancer biology, where altered expression of cell adhesion molecules can influence tumor metastasis and immune evasion. As a result, researchers have focused on the recombinant production of CLMP to facilitate in-depth studies of its structural and functional properties. Recombination techniques allow for the generation of highly pure and active CLMP, enabling scientists to investigate its molecular interactions and pathways in detail. The ability to produce CLMP in a controlled laboratory environment paves the way for potential therapeutic applications and the development of novel cancer diagnostics. Furthermore, studying CLMP's role in cell signaling may provide insights into how tumors utilize adhesion mechanisms to spread, ultimately aiding in the discovery of new strategies for cancer treatment. Overall, the research into CLMP and its recombination is pivotal for advancing our understanding of cell adhesion dynamics and their impact on health and disease.

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