Analytical Data
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Gene name
GPR62
- Application
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Alternative Names
(G-protein coupled receptor GPCR8)(hGPCR8)(G-protein coupled receptor KPG_005)
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Species
Human
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Source
E. coli
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BZJ7
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Expression Region
1-368aa
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Molecular Weight
39.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GPR62, a member of the G protein-coupled receptor (GPCR) family, has garnered significant interest in biomedical research due to its potential roles in various physiological processes and diseases. Despite being classified as an orphan receptor, meaning its endogenous ligand remains unidentified, preliminary studies suggest that GPR62 might be involved in modulating neuronal activity, influencing mood disorders, and contributing to the regulation of circadian rhythms. Its expression is particularly noted in the central nervous system, sparking curiosity about its implications in neurodegenerative diseases. To clarify the function and signaling pathways associated with GPR62, researchers have ventured into generating recombinant GPR62 proteins. These recombinant proteins facilitate the exploration of GPR62's structural, functional, and biochemical properties, enabling the identification of possible ligands and downstream signaling cascades. Understanding GPR62's mechanisms could reveal novel therapeutic targets for treating disorders that involve dysregulation of GPCR signaling. Furthermore, the development of pharmacological tools and agonists/antagonists specific to GPR62 may pave the way for innovative strategies in drug discovery, particularly for conditions currently lacking effective treatments. Thus, ongoing research on recombinant GPR62 proteins is critical not only for elucidating its biological roles but also for advancing the field of molecular pharmacology and improving therapeutic interventions.
