Cat: PA2000-3734

Recombinant Human OLIG1 Protein,His

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Analytical Data

  • 基因名

    OLIG1

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    OLIG1;BHLHB6;BHLHE21;Oligodendrocyte transcription factor 1

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q8TAK6

  • 表达区间

    17-105aa

  • 氨基酸序列

    MLRPQRPGDLQLGASLYELVGYRQPPSSSSSSTSSTSSTSSSSTTAPLLPKAAREKPEAPAEPPGPGPGSGAHPGGSARPDAKEEQQQQ

  • 分子量

    11.1 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

OLIG1, a member of the oligodendrocyte transcription factor family, plays a critical role in the development and maintenance of oligodendrocytes, the myelinating cells in the central nervous system. Research has shown that OLIG1 is essential for proper neural development, influencing the differentiation of oligodendrocyte progenitor cells and the formation of myelin sheaths around axons. Mutations or dysregulation of OLIG1 have been implicated in various neurological disorders, including multiple sclerosis and leukodystrophies, highlighting its significance in both normal and pathological conditions. The recombinant protein of OLIG1 allows researchers to investigate its functional properties, interaction with other proteins, and downstream signaling pathways in greater detail. Studies involving OLIG1 recombinant protein are crucial for understanding its mechanisms of action and potential therapeutic targets, as well as for exploring its role in neuroprotection and repair processes following injury. Additionally, OLIG1's involvement in the reprogramming of other cell types into oligodendrocyte-like cells suggests its potential in regenerative medicine and cell therapy for demyelinating diseases. Overall, the study of OLIG1 recombinant protein provides valuable insights into oligodendrocyte biology, with significant implications for developing novel treatments for neurological disorders.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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