Analytical Data
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基因名
GPR1
- Application
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别名
CMKLR2; GPR1; Chemerin-like receptor 2; Chemerin chemokine-like receptor 2; Chemokine-like receptor 2; G-protein coupled receptor 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P46091
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表达区间
1-355aa
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氨基酸序列
MEDLEETLFEEFENYSYDLDYYSLESDLEEKVQLGVVHWVSLVLYCLAFVLGIPGNAIVIWFTGFKWKKTVTTLWFLNLAIADFIFLLFLPLYISYVAMNFHWPFGIWLCKANSFTAQLNMFASVFFLTVISLDHYIHLIHPVLSHRHRTLKNSLIVIIFIWLLASLIGGPALYFRDTVEFNNHTLCYNNFQKHDPDLTLIRHHVLTWVKFIIGYLFPLLTMSICYLCLIFKVKKRSILISSRHFWTILVVVVAFVVCWTPYHLFSIWELTIHHNSYSHHVMQAGIPLSTGLAFLNSCLNPILYVLISKKFQARFRSSVAEILKYTLWEVSCSGTVSEQLRNSETKNLCLLETAQ
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分子量
41.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GPR1, a G protein-coupled receptor (GPCR), has garnered significant interest in the field of molecular biology and pharmacology due to its potential roles in various physiological processes. Initially identified in yeast as a regulatory protein involved in nutrient sensing and stress response, it has since been shown to exhibit similar functions in higher organisms, including humans. Research indicates that GPR1 may play critical roles in mediating cellular responses to different stimuli, potentially influencing metabolic pathways and hormonal signaling. The importance of GPR1 is further underscored by its involvement in several health conditions, including obesity, diabetes, and cardiovascular diseases. Thus, understanding the structure and function of GPR1, particularly through the study of its recombinant protein, is crucial for elucidating its mechanisms of action and exploring its therapeutic potential. Recombinant GPR1 can be used for various applications, including drug screening, functional assays, and structural studies, aiming to identify novel ligands that could modulate its activity. As the field advances, the investigation of GPR1 is expected to contribute significantly to the discovery of new therapeutic strategies targeting metabolic disorders and other related diseases.
