Analytical Data
-
Gene name
KERA
- Application
-
Alternative Names
KERA；SLRR2B；Keratocan
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
O60938
-
Expression Region
21-352aa
-
AA Sequence
RSVRQVYEVH DSDDWTIHDF ECPMECFCPP SFPTALYCEN RGLKEIPAIP SRIWYLYLQN NLIETIPEKP FENATQLRWI NLNKNKITNY GIEKGALSQL KKLLFLFLED NELEEVPSPL PRSLEQLQLA RNKVSRIPQG TFSNLENLTL LDLQNNKLVD NAFQRDTFKG LKNLMQLNMA KNALRNMPPR LPANTMQLFL DNNSIEGIPE NYFNVIPKVA FLRLNHNKLS DEGLPSRGFD VSSILDLQLS HNQLTKVPRI SAHLQHLHLD HNKIKSVNVS VICPSPSMLP AERDSFSYGP HLRYLRLDGN EIKPPIPMAL MTCFRLLQAV II
-
Molecular Weight
40.5 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
KERA, or keratin-associated protein, has garnered significant attention in recent years due to its essential role in forming the structural framework of hair, nails, and skin. As a key component of the keratinocyte layer, KERA contributes to the resilience and protective nature of epithelial tissues. Research into KERA's recombinant proteins is driven by the desire to understand their functional properties, molecular mechanisms, and potential applications in tissue engineering and regenerative medicine. The use of recombinant DNA technology allows for large-scale production of KERA proteins, facilitating exhaustive biochemical studies and giving insights into their interactions with other cellular components. Furthermore, the exploration of KERA’s role in various pathological conditions, such as skin disorders and hair loss, opens new avenues for therapeutic development. By harnessing the biotechnological advancements in protein engineering, researchers anticipate the ability to design novel biomaterials that mimic natural keratin structures, enhancing wound healing and promoting skin regeneration. Overall, the investigation of KERA recombinant proteins stands at the intersection of basic science and applied research, promising to yield significant contributions to dermatology and cosmetic industries, as well as broader implications in biomedicine.
