Cat: PA2000-3992

Recombinant Human DEFB129 Protein,His

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Analytical Data

  • 基因名

    DEFB129

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    DEFB129;C20orf87;DEFB29;Beta-defensin 129

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q9H1M3

  • 表达区间

    20-183aa

  • 氨基酸序列

    IGLRRCLMGLGRCRDHCNVDEKEIQKCKMKKCCVGPKVVKLIKNYLQYGTPNVLNEDVQEMLKPAKNSSAVIQRKHILSVLPQIKSTSFFANTNFVIIPNATPMNSATISTMTPGQITYTATSTKSNTKESRDSATASPPPAPPPPNILPTPSLELEEAEEQAAASFLEQKLISEEDLNSAVD

  • 分子量

    21.8 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

DEFB129, a member of the defensin family of proteins, is primarily expressed in human tissues, particularly in the male reproductive system. As an antimicrobial peptide, it plays a pivotal role in the innate immune response by exhibiting broad-spectrum activity against various pathogens, including bacteria, viruses, and fungi. Research on DEFB129 has gained traction due to its potential applications in therapeutic development, specifically in enhancing immune responses and serving as a model for designing novel antimicrobial agents. Additionally, investigations into the structural properties of DEFB129 have provided insights into its mechanism of action, revealing that its efficacy stems from its ability to disrupt microbial membranes. Given the rising global concern regarding antibiotic resistance, DEFB129 presents a promising alternative in combating resistant strains. Recent studies have also explored the role of DEFB129 in reproductive health, suggesting that it may be crucial for maintaining the balance of the microflora in the male reproductive tract. Continuous research aims to elucidate the clinical implications of DEFB129, potentially leading to breakthroughs in both infectious disease management and reproductive medicine. Through recombinant protein expression systems, scientists are now able to produce DEFB129 for various experimental applications, facilitating deeper investigations into its biological functions and therapeutic potential.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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