Analytical Data
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Gene name
MYH8
- Application
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Alternative Names
MYH8；Myosin-8
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P13535
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Expression Region
全长
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AA Sequence
full
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MYH8, a member of the myosin gene family, encodes a muscle-specific myosin heavy chain predominantly expressed in the fast-twitch skeletal muscle fibers. Research into MYH8 has gained significance due to its crucial role in muscle development and function, as well as its implications in muscle-related diseases, including myopathies and conditions like congenital myopathy. Recent studies have highlighted that mutations in MYH8 can lead to altered myosin function, resulting in impaired muscle contraction and overall muscle integrity. The recombinant MYH8 protein is significant for studying its biophysical properties and interactions within muscle tissues. It serves as a vital tool for understanding the mechanistic pathways involved in muscle contractions and the potential pathophysiological effects of MYH8 mutations. The production of recombinant MYH8 protein allows for detailed examination of its structure-function relationship, providing insights into muscle function at the molecular level. This research is not only pivotal for advancing our understanding of muscle biology but also holds potential therapeutic implications for regenerative medicine and treatment strategies for muscle disorders. Overall, the study of MYH8 recombinant protein is essential for unraveling the complexities of muscle physiology and the development of targeted therapies.
