Analytical Data
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基因名
HLX1
- Application
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别名
H2.0 like homeo box 1; H2.0 like homeobox 1; H2.0 like homeobox 1 Drosophila; H2.0-like homeobox protein; HB24; HLX; HLX_HUMAN; Homeobox protein HB24; Homeobox protein HLX1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q14774
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表达区间
1-488aa
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氨基酸序列
MFAAGLAPFYASNFSLWSAAYCSSAGPGGCSFPLDPAAVKKPSFCIADILHAGVGDLGAAPEGLAGASAAALTAHLGSVHPHASFQAAARSPLRPTPVVAPSEVPAGFPQRLSPLSAAYHHHHPQQQQQQQQPQQQQPPPPPRAGALQPPASGTRVVPNPHHSGSAPAPSSKDLKFGIDRILSAEFDPKVKEGNTLRDLTSLLTGGRPAGVHLSGLQPSAGQFFASLDPINEASAILSPLNSNPRNSVQHQFQDTFPGPYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGAPAADGEQDERSPSRSEGEAESESSDSESLDMAPSDTERTEGSERSLHQTTVIKAPVTGALITASSAGSGGSSGGGGNSFSFSSASSLSSSSTSAGCASSLGGGGASELLPATQPTASSAPKSPEPAQGALGCL
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分子量
77.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HLX1, or Homeobox Protein HLX, is a transcription factor belonging to the homeobox gene family, which plays a crucial role in embryonic development and cellular differentiation. It is primarily expressed in the early stages of hematopoiesis and has been linked to various processes, including organogenesis and tissue regeneration. Research indicates that HLX1 is implicated in several important biological systems, including the immune response and hematopoietic lineage specification. Abnormal expression of HLX1 has been associated with various diseases, including leukemia and other hematological disorders, suggesting its potential as a biomarker for disease diagnosis and prognosis. The study of recombinant HLX1 protein has gained traction as it allows for better understanding of its functional roles and regulatory mechanisms in cellular processes. By producing HLX1 in a recombinant form, researchers aim to investigate its interactions with other proteins, identify its downstream targets, and elucidate its involvement in specific signaling pathways. This research not only enhances our understanding of HLX1's biological significance but also opens avenues for therapeutic interventions in HLX1-associated diseases. Additionally, the generation of recombinant HLX1 provides a platform for developing novel drugs and treatment strategies, further emphasizing its relevance in both basic research and clinical applications. Overall, advancing the knowledge of HLX1 through recombinant protein studies is pivotal for understanding its contribution to health and disease, paving the way for innovative approaches in regenerative medicine and cancer therapy.
