Analytical Data
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基因名
HOXB3
- Application
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别名
Homeo box 2G ; Homeo box B3; Homeobox B3; Homeobox protein Hox-2.7; Homeobox protein Hox-2G; Homeobox protein Hox-B3; Homeobox protein HoxB3; Hox 2.7; HOX 2G; HOX2; Hox2.7; HOX2G; HOXB3; HXB3_HUMAN
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P14651
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表达区间
1-431aa
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氨基酸序列
MQKATYYDNAAAALFGGYSSYPGSNGFGFDVPPQPPFQAATHLEGDYQRSACSLQSLGNAAPHAKSKELNGSCMRPGLAPEPLSAPPGSPPPSAAPTSATSNSSNGGGPSKSGPPKCGPGTNSTLTKQIFPWMKESRQTSKLKNNSPGTAEGCGGGGGGGGGGGSGGSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAGSPPQPMQSTAGFMNALHSMTPSYESPSPPAFGKAHQNAYALPSNYQPPLKGCGAPQKYPPTPAPEYEPHVLQANGGAYGTPTMQGSPVYVGGGGYADPLPPPAGPSLYGLNHLSHHPSGNLDYNGAPPMAPSQHHGPCEPHPTYTDLSSHHAPPPQGRIQEAPKLTHL
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分子量
73.81 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Homeobox gene family members, particularly HOXB3, play a crucial role in developmental processes and cellular differentiation. HOXB3 is part of the HOX gene cluster, which is known to regulate gene expression during embryogenesis and is essential for the proper formation of various tissues and organs. The implications of HOXB3 in cancer and various genetic disorders have garnered significant research interest, as alterations in HOX gene expression can lead to abnormal cell proliferation and tumorigenesis. Previous studies have shown that HOXB3 is involved in pathways influencing neuronal development and may also participate in inflammatory responses. The recombinant protein of HOXB3 is being studied not only to further understand its biological functions but also to explore its potential applications in therapeutic strategies. By harnessing recombinant DNA technology, researchers can produce HOXB3 in the laboratory, allowing for in-depth analysis of its structural and functional properties. This ongoing research aids in elucidating the mechanisms through which HOXB3 exerts its effects in normal physiology and disease states, paving the way for potential interventions in conditions where HOXB3 plays a pivotal role. Overall, studying HOXB3 recombinant protein offers valuable insights into its biological significance and potential therapeutic applications in oncology and regenerative medicine.












