Analytical Data
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基因名
HOXB13
- Application
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别名
HOXB13;Homeobox Protein Hox-B13
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q92826
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表达区间
1-284aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMEPGNYA TLDGAKDIEG LLGAGGGRNL VAHSPLTSHP AAPTLMPAVN YAPLDLPGSA EPPKQCHPCP GVPQGTSPAP VPYGYFGGGY YSCRVSRSSL KPCAQAATLA AYPAETPTAG EEYPSRPTEF AFYPGYPGTY QPMASYLDVS VVQTLGAPGE PRHDSLLPVD SYQSWALAGG WNSQMCCQGE QNPPGPFWKA AFADSSGQHP PDACAFRRGR KKRIPYSKGQ LRELEREYAA NKFITKDKRR KISAATSLSE RQITIWFQNR RVKEKKVLAK VKNSATP
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分子量
33 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HOXB13 is a member of the homeobox gene family, which plays a crucial role in the regulation of gene expression during embryonic development and cellular differentiation. Recent studies have increasingly highlighted the significance of HOXB13 in cancer biology, particularly its association with prostate cancer, where specific mutations have been linked to hereditary risks. The investigation of HOXB13 recombinant proteins has garnered interest as it allows researchers to study the functional aspects of this transcription factor in detail. By producing HOXB13 in a recombinant form, scientists can explore its DNA-binding properties, interaction with other proteins, and its role in transcriptional regulation. This research not only aims to unravel the molecular mechanisms underlying HOXB13's contribution to prostate cancer pathogenesis but also seeks to identify potential therapeutic targets. Understanding the structure and function of HOXB13 through recombinant proteins could pave the way for developing strategies to modulate its activity, potentially leading to better diagnostic and treatment options for individuals at risk of or affected by prostate cancer. Overall, the study of HOXB13 recombinant proteins stands at the intersection of developmental biology and oncology, holding promise for advancing our knowledge of gene regulation in cancer and improving patient outcomes.
