Analytical Data
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基因名
Il1f5
- Application
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别名
AI413231; Family of interleukin 1 delta; FIL1; FIL1 delta; FIL1(DELTA); FIL1D; Fil1delta; I36RA_HUMAN; IL 1 delta; IL 1 related protein 3; IL 1F5 (IL 1HY1. FIL1 delta. IL 1RP3. IL 1L1. IL 1 delta); Il 1h3; IL 1HY1; IL 1L1; IL 1ra homolog; IL 1ra homolog. IL1F5 (Canonical product IL 1F5a); IL 1RP3; IL-1 delta; IL-1-related protein 3; IL-1F5; IL-1HY1; IL-1L1; IL-1ra homolog 1; IL-1RP3; IL1F5; IL1HY1; IL1L1; IL1RP3; IL36RA; IL36RN; Interleukin 1 delta; Interleukin 1 family member 5 (delta); Interleukin 1 family member 5
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UBH0
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表达区间
2-155aa
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氨基酸序列
VLSGALCFRM KDSALKVLYL HNNQLLAGGL HAGKVIKGEE ISVVPNRWLD ASLSPVILGV QGGSQCLSCG VGQEPTLTLE PVNIMELYLG AKESKSFTFY RRDMGLTSSF ESAAYPGWFL CTVPEADQPV RLTQLPENGG WNAPITDFYF QQCD
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分子量
16.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
IL1F5, also known as Interleukin 1 Family Member 5 or IL-33, is a cytokine that plays a pivotal role in the immune response and inflammation. Studies have shown that IL1F5 is involved in the regulation of Th2 responses, making it crucial in allergic diseases, asthma, and other inflammatory conditions. Researchers are increasingly focused on this cytokine due to its potential as a therapeutic target for a variety of disorders, including autoimmune diseases and cancers. The recombinant expression of IL1F5 allows for detailed investigations into its biological functions, signaling pathways, and interactions with other immune mediators. By producing and characterizing this recombinant protein, scientists aim to elucidate its role in modulating immune responses, which could lead to the development of novel therapeutic strategies. Understanding the structure-function relationship of IL1F5 through recombinant technology not only enhances our knowledge of its physiological roles but also paves the way for future clinical applications. As a result, IL1F5 is emerging as a significant focus in immunological research, potentially influencing the treatment paradigms for endocrine dysregulation and inflammatory diseases.
