Recombinant Human LCN2 Protein，His

Lipocalin 2 (LCN2), also known as 24p3 or NGAL (neutrophil gelatinase-associated lipocalin), is a small extracellular protein that plays crucial roles in various biological processes, including iron homeostasis, immune response, and inflammation. It is primarily produced by neutrophils and various epithelial cells in response to inflammatory stimuli. The interest in LCN2 has surged due to its implications in several disease states, including cancer, renal injury, and infections. Its ability to bind iron and transport it in the extracellular environment makes it a key player in regulating the iron levels within tissues, thereby influencing microbial growth and the host's immune response. Furthermore, LCN2 is regarded as a potential biomarker for acute kidney injury and is being studied for its diagnostic and therapeutic potentials. The production of recombinant LCN2 proteins through genetic engineering techniques has facilitated the detailed exploration of its biological functions and interactions. By studying the structure-function relationship of LCN2, researchers aim to uncover its mechanistic roles in pathophysiological conditions and to develop novel therapeutic strategies that leverage its properties. Overall, the recombinant expression and characterization of LCN2 hold promise not only for advancing our understanding of its biological significance but also for its potential applications in clinical diagnostics and therapeutics.