Analytical Data
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基因名
BSG
- Application
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别名
BSG;Basigin
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P35613
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表达区间
138-323aa
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氨基酸序列
EPGTVFTTVEDLGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLA
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分子量
49.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of BSG (Basigin, or CD147) recombinant proteins has gained significant attention in recent years due to its crucial role in various biological processes and disease pathologies. BSG is a transmembrane glycoprotein belonging to the immunoglobulin superfamily, known for its involvement in cell adhesion, intercellular signaling, and interactions with various ligands, such as cyclophilins and MCT (monocarboxylate transporters). Research has shown that BSG is upregulated in several cancers, including breast, lung, and colorectal cancers, where it contributes to tumor progression, metastasis, and immune evasion. Additionally, BSG plays a vital role in the development of the central nervous system and is implicated in inflammatory responses and autoimmune diseases. The generation of recombinant BSG proteins has allowed scientists to investigate its functional properties and interactions at a molecular level. These studies facilitate the understanding of BSG's role in physiological and pathological conditions, potentially leading to targeted therapeutic strategies. Furthermore, recombinant BSG proteins serve as valuable tools in the development of diagnostics and vaccines, enhancing our knowledge of immune responses and pathogen interactions. Overall, the exploration of BSG recombinant proteins represents a promising avenue for advancing our understanding of fundamental biological processes and developing novel therapeutic interventions.












