Recombinant Human KIAA0101 Protein，His

KIAA0101, also known as PTIP (p53-regulated transcriptional intermediary factor), is a protein that has gained considerable attention in molecular biology and cancer research due to its implications in DNA repair, cell cycle regulation, and tumorigenesis. The gene encoding KIAA0101 is located on chromosome 14 and plays a significant role in mediating the response to DNA damage by facilitating the recruitment of repair factors to sites of DNA lesions. Its interaction with various proteins, including those involved in the p53 pathway, underscores its potential role as a regulatory hub in cellular stress responses. Dysregulation of KIAA0101 has been implicated in several cancers, making it a candidate for further exploration as a biomarker for tumor progression and a potential target for therapeutic intervention. Recent studies have focused on elucidating the structural and functional aspects of KIAA0101, particularly its recombinantly expressed forms, to better understand its mechanistic roles in cellular processes and its contribution to oncogenesis. This research aims not only to clarify the biological functions of KIAA0101 but also to explore its potential as a therapeutic target in cancer treatment, offering prospects for novel strategies in oncotherapy. Additionally, KIAA0101’s involvement in maintaining genomic integrity positions it as a vital component in the study of cancer biology, highlighting the need for continued research to fully unravel its contributions to cellular physiology and pathology.