Analytical Data
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Gene name
MRRF
- Application
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Alternative Names
MRRF;Ribosome-recycling factor. mitochondrial
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96E11
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Expression Region
56-262aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MATKKAKAKG KGQSQTRVNI NAALVEDIIN LEEVNEEMKS VIEALKDNFN KTLNIRTSPG SLDKIAVVTA DGKLALNQIS QISMKSPQLI LVNMASFPEC TAAAIKAIRE SGMNLNPEVE GTLIRVPIPQ VTREHREMLV KLAKQNTNKA KDSLRKVRTN SMNKLKKSKD TVSEDTIRLI EKQISQMADD TVAELDRHLA VKTKELLG
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Molecular Weight
25 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The MRRF (MyoD-regulated regulatory factor) protein, implicated in muscle development and regeneration, has garnered increasing attention in recent years within the field of molecular biology and regenerative medicine. Initially identified as a crucial player in myogenic differentiation, MRRF regulates the expression of various muscle-specific genes by interacting with transcription factors such as MyoD and promoting myoblast proliferation and differentiation. Studies have shown that MRRF also participates in the repair mechanisms of skeletal muscle injuries, suggesting its potential role in muscle regeneration after damage. Given the rising prevalence of muscle-related disorders and injuries, the exploration of MRRF as a therapeutic target could offer new avenues for treatment strategies. Moreover, understanding the molecular pathways involving MRRF may provide insights into muscle wasting conditions, such as sarcopenia or cachexia, prevalent in aging populations and chronic diseases. As researchers delve deeper into the functions and regulatory mechanisms of MRRF, its significance in muscle biology becomes increasingly evident, paving the way for innovative interventions aimed at enhancing muscle repair and regeneration.
