Analytical Data
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基因名
LCE5A
- Application
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别名
LCE5A; LEP18; SPRL5ALate cornified envelope protein 5A; Late envelope protein 18; Small proline-rich-like epidermal differentiation complex protein 5A
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5TCM9
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表达区间
1-118aa
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氨基酸序列
MSCQQSQQQCQPPPKCTPKCPPKCTPKCPPKCPPKCPPQCSAPCPPPVSSCCGSSSGGCCSSEGGGCCLSHHRPRQSLRRRPQSSSCCGSGSGQQSGGSSCCHSSGGSGCCHSSGGCC
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分子量
39.38 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
LCE5A, or Late Cornified Envelope 5A, is a member of the LCE gene family, which is primarily expressed in the epidermis and plays a crucial role in skin barrier function and integrity. Research into LCE5A has gained momentum due to its potential implications in various skin disorders, such as psoriasis, eczema, and other inflammatory skin diseases. The protein is believed to participate in the cornification process, helping to regulate keratinocyte differentiation and promoting the formation of a robust stratum corneum. Moreover, studies have indicated that LCE5A may be involved in the immune response of the skin, contributing to the organ’s defense against environmental stressors and pathogens. Genetic variations and changes in the expression levels of LCE5A have been associated with altered susceptibility to skin diseases, making it an important target for understanding the molecular mechanisms behind these conditions. Consequently, exploring the recombinant expression of LCE5A protein provides opportunities for developing novel therapeutic strategies and skin-care products that could enhance skin health and treat related disorders. The research focuses not only on the functional characterization of LCE5A but also on its potential use in regenerative medicine and dermatological applications, highlighting the significance of this protein in both basic and translational research.
