Analytical Data
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Gene name
Rab44
- Application
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Alternative Names
Rab44；Ras-related Protein Rab-44
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q7Z6P3
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Expression Region
1-723aa
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AA Sequence
MQDVLEAKER EVQRLAEGQR ELEAQLSHLR STHQEAASEN QQLQEAKRDL AGRLEEVRGQ LQVTRGRLDA ARGRVSWQVE EKLRQVAAIP GLGFPGAGEK TPDPQAASPE EAPLPGLFGD NDDWDQLLSN FGSPPHGALQ LCWSPPPTPR ATSGPQTPRV VRQISISEPQ AFLFGQEPSS DPDGAPRTPP GVTFSAKDNK GVDPHEQDIR AEQPVEPHDP DPNQEPGSTP EGRLLWGLSG SLVAPAFKVL IPLEDGPPPP ANSPPPQAPA GSSKQIQASD PDDKGPGQRD ALQQDLHATG SEPRLGTQRA RALTLGPAEP FQGLEFVGPV PTERLEQGQA GPAVQEGLPE GLREAHGQVL GLGELSAFPH QELEEEPRSE EGKQEGRGGQ DLSSEQSEQS VEAHGLETAH SELPQQDSLL VSLPSATPQA QVEAEGPTPG KSAPPRGSPP RGAQPGAGAG PQEPTQTPPT MAEQEAQPRP SLTTAHAEEQ GPPHSREPRA ESRLEDPGMD SREAGLTPSP GDPMAGGGPQ ANPDYLFHVI FLGDSNVGKT SFLHLLHQNS FATGLTATVG VDFRVKTLLV DNKCFVLQLW DTAGQERYHS MTRQLLRKAD GVVLMYDITS QESFAHVRYW LDCLQDAGSD GVVILLLGNK MDCEEERQVS VEAGQQLAQE LGVYFGECSA ALGHNILEPV VNLARSLRMQ EEGLKDSLVK VAPKRPPKRF GCC
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Rab44 is a member of the Rab family of small GTPases, which are crucial regulators of membrane trafficking within eukaryotic cells. This protein is implicated in various cellular processes, including endocytic and exocytic pathways, autophagy, and intracellular signaling. Research indicates that Rab44 plays a significant role in the regulation of mitochondrial dynamics and function, linking it to processes such as apoptosis and cellular stress responses. Recent studies have suggested a potential association between Rab44 and certain pathological conditions, including neurodegenerative diseases and cancer, highlighting its relevance in health and disease. The experimental production of recombinant Rab44 protein allows researchers to investigate its biochemical properties, functional roles, and interactions with other cellular components in detail. By exploring the mechanistic pathways governed by Rab44, scientists aim to enhance the understanding of its contributions to cellular homeostasis and investigate its potential as a therapeutic target. Overall, the study of recombinant Rab44 protein is crucial for elucidating the fundamental biological functions of this GTPase and its implications in various physiological and pathological contexts.
