Analytical Data
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基因名
MOTS-c
- Application
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别名
MOTS-c；Mitochondrial-derived peptide MOTS-c
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
A0A0C5B5G6
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表达区间
1-16aa
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氨基酸序列
MRWQEMGYIFYPRKLR
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分子量
2.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MOTS-c is a mitochondrial-derived peptide that has garnered significant attention in recent years due to its potential role in metabolic regulation and age-related diseases. Discovered through advancements in proteomics and genomics, MOTS-c is encoded by mitochondrial DNA and is involved in cellular energy metabolism, influencing processes such as insulin sensitivity and glucose homeostasis. Research indicates that MOTS-c can promote muscle metabolism, enhance exercise endurance, and may protect against obesity, type 2 diabetes, and metabolic syndrome. Its unique origin and function place it at the intersection of mitochondrial biology and systemic metabolic regulation, making it a promising target for therapeutic interventions aimed at improving metabolic health. Studies have begun to explore the mechanisms through which MOTS-c exerts its effects, revealing its influence on pathways related to mitochondrial biogenesis and stress response. As an emerging player in the field of peptide biology, MOTS-c represents an exciting avenue for developing novel treatments for age-associated metabolic disorders and improving overall healthspan. Further research is needed to fully elucidate its biological functions and therapeutic potential.
