Analytical Data
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Gene name
NXT2
- Application
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Alternative Names
NXT2;NTF2-related export Protein 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NPJ8-3
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Expression Region
1-197aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMRKYRS HWSQGDREGY QRRSNYYEGP HTSHSSPADR TREEVVTPTL PEHTATRSQM ATSLDFKTYV DQACRAAEEF VNIYYETMDK RRRALTRLYL DKATLIWNGN AVSGLDALNN FFDTLPSSEF QVNMLDCQPV HEQATQSQTT VLVVTSGTVK FDGNKQHFFN QNFLLTAQST PNNTVWKIAS DCFRFQDWSS S
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Molecular Weight
25 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NXT2 (Nuclear Export Transport Factor 2) is a crucial protein involved in the export of RNA and ribonucleoprotein complexes from the nucleus to the cytoplasm, playing a significant role in gene expression regulation and cellular signaling. Research on NXT2 has gained momentum due to its implications in various biological processes and diseases. Abnormal NXT2 functioning has been linked to viral infections, cancer progression, and other disorders, highlighting its potential as a therapeutic target. Scientists have been particularly interested in characterizing its structure, understanding its mechanism of action, and exploring its interactions with RNA and other proteins involved in nuclear export. This knowledge can advance our understanding of the fundamental cellular machinery and may facilitate the development of novel strategies for treating diseases associated with dysregulated nucleocytoplasmic transport. Recent developments in recombinant protein technology have allowed for the production and purification of NXT2, enabling detailed functional studies and structure-function analyses. These advancements are paving the way for innovative research opportunities, including drug design and targeting specific pathways modulated by NXT2. Overall, the study of NXT2 and its recombinant variants is becoming increasingly vital in molecular biology, with the potential to unlock new insights into cellular dynamics and therapeutic applications.
