Analytical Data
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Gene name
CCNT1
- Application
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Alternative Names
CCNT1；Cyclin-T1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O60563
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Expression Region
86.7 kDa
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AA Sequence
MEGERKNNNKRWYFTREQLENSPSRRFGVDPDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFTQFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKTPNRLKRIWNWRACEAAKKTKADDRGTDEKTSEQTILNMISQSSSDTTIAGLMSMSTSTTSAVPSLPVSEESSSNLTSVEMLPGKRWLSSQPSFKLEPTQGHRTSENLALTGVDHSLPQDGSNAFISQKQNSKSVPSAKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAYAAQNLLSHHDSHSSVILKMPIEGSENPERPFLEKADKTALKMRIPVAGGDKAASSKPEEIKMRIKVHAAADKHNSVEDSVTKSREHKEKHKTHPSNHHHHHNHHSHKHSHSQLPVGTGNKRPGDPKHSSQTSNLAHKTYSLSSSFSSSSSTRKRGPSEETGGAVFDHPAKIAKSTKSSSLNFSFPSLPTMGQMPGHSSDTSGLSFSQPSCKTRVPHSKLDKGPTGANGHNTTQTIDYQDTVNMLHSLLSAQGVQPTQPTAFEFVRPYSDYLNPRSGGISSRSGNTDKPRPPPLPSEPPPPLPPLPK
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Molecular Weight
86.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CCNT1, or Cyclin-Dependent Kinase-Activating Cyclin T1, is a crucial protein involved in the regulation of the cell cycle and transcriptional control. It plays an essential role in the activation of cyclin-dependent kinases (CDKs), which are pivotal for cell proliferation and function. Research has identified CCNT1 as a significant player in various cellular processes, including gene transcription regulation and the modulation of RNA polymerase II activity. Additionally, CCNT1 is implicated in several diseases, particularly cancers, where its dysregulation may contribute to uncontrolled cell growth. The study of CCNT1 recombinant protein has gained attention due to its potential as a therapeutic target and its utility in understanding cell cycle dynamics. By producing and characterizing CCNT1 in recombinant form, researchers aim to delineate its biochemical properties, investigate its interactions with other proteins, and explore its role in the pathogenesis of various diseases. This research not only enhances our understanding of CCNT1's function but also lays the groundwork for potential innovations in cancer treatment and other therapeutic strategies targeting cell cycle regulation. Furthermore, the development of CCNT1 as a recombinant protein provides insights into its structural and functional attributes, facilitating the exploration of small molecules or biologics that can modulate its activity within the therapeutic landscape. Overall, CCNT1 continues to be a significant focus in molecular biology and oncology, offering promising avenues for therapeutic intervention and deepening our understanding of cellular regulation.
