Analytical Data
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基因名
MRO
- Application
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别名
B29; beside the Ma29 deletion; C18orf3; Male-specific transcription in the developing reproductive organs; Mro; MSTRO_HUMAN; Protein B29; Protein maestro
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BYG7
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表达区间
1-248 aa
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氨基酸序列
MDQRQRRILG QPLSIPTSQP KQKRTSMISF FSKVSWKLRF QKREPLKNVF FILAERARDP SAKKRHMAMR NLGTMAYEAP DKVRKYKKIV LDLLVYGLYD PVNLEVIHES MKTLTVVLGK IQGKGLGSFF IDITLQTRTL LDDENDSLRY SAFVLFGQLA AFAGRKWKKF FTSQVKQTRD SLLIHLQDRN PQVAKACKTT FQACSPYLKL KEEYSFQSEE DQRNTKLYQQ LSHYHPEILQ FFYANKIL
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分子量
29.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MRO (Mitochondrial Ribosomal Protein) reorganization has emerged as a significant area of research due to its crucial role in mitochondrial function and cellular metabolism. Mitochondria, known as the powerhouse of the cell, are responsible for energy production through oxidative phosphorylation, which requires a finely tuned balance of mitochondrial and nuclear gene expression. The MRO proteins are essential components of the mitochondrial ribosome, facilitating translation during protein synthesis. Recent studies have revealed that alterations in the expression and function of MRO proteins are linked to various metabolic disorders and mitochondrial diseases, including diabetes, neurodegenerative conditions, and certain myopathies. Additionally, MRO proteins are now recognized for their involvement in stress responses and apoptosis, further highlighting their importance in maintaining cellular homeostasis. The investigation of MRO protein dynamics and their interactions with other mitochondrial components can provide insights into the molecular mechanisms underlying mitochondrial dysfunction. This research may pave the way for novel therapeutic strategies aimed at rectifying mitochondrial impairments, emphasizing the relevance of MRO proteins in health and disease. Understanding how MRO reorganization influences mitochondrial activity and overall cellular physiology remains a key challenge in contemporary biomedical research, making it a vital topic of interest in the fields of genetics, molecular biology, and medicine.












