Analytical Data
-
Gene name
MRPS17
- Application
-
Alternative Names
1810006P02Rik; 28S ribosomal protein S17; 28S ribosomal protein S17 mitochondrial; HSPC011; mitochondrial; Mitochondrial ribosomal protein S17; MRP S17; MRP-S17; mrps17; OTTHUMP00000209315; OTTMUSP00000034583; OTTMUSP00000034585; OTTMUSP00000034586; OTTMUSP00000034588; OTTMUSP00000034590; OTTMUSP00000034591; OTTMUSP00000034592; RPMS17; RT17_HUMAN; S17mt
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9Y2R5
-
Expression Region
21-130 aa
-
AA Sequence
KMQKTAKVRV TRLVLDPYLL KYFNKRKTYF AHDALQQCTV GDIVLLRALP VPRAKHVKHE LAEIVFKVGK VIDPVTGKPC AGTTYLESPL SSETTQLSKN LEELNISSAQ
-
Molecular Weight
14.5 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MRPS17 (Mitochondrial Ribosomal Protein S17) is a critical component of the mitochondrial ribosome, which plays a vital role in protein synthesis within mitochondria. Its primary function involves translating mitochondrial mRNA into proteins essential for oxidative phosphorylation, a process crucial for cellular energy production. Research has shown that MRPS17 is not only important for mitochondrial function but also implicated in several diseases, including mitochondrial disorders and certain cancers. Given the increasing recognition of mitochondrial dysfunction in various pathologies, understanding the structure, function, and regulation of MRPS17 is paramount. Recent studies have focused on the reconstitution of MRPS17 as a recombinant protein to elucidate its molecular interactions and assess its stability and functionality in vitro. This research aims to explore the protein's potential as a therapeutic target, as well as to provide insights into its involvement in mitochondrial biogenesis and dynamics. By investigating MRPS17, researchers hope to contribute to the broader understanding of mitochondrial biology and its implications for human health and disease.
