Analytical Data
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基因名
RAB8B
- Application
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别名
RAB8B;Ras-related Protein Rab-8B
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q92930
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表达区间
1-204aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMAKTYDY LFKLLLIGDS GVGKTCLLFR FSEDAFNTTF ISTIGIDFKI RTIELDGKKI KLQIWDTAGQ ERFRTITTAY YRGAMGIMLV YDITNEKSFD NIKNWIRNIE EHASSDVERM ILGNKCDMND KRQVSKERGE KLAIDYGIKF LETSAKSSAN VEEAFFTLAR DIMTKLNRKM NDSNSAGAGG PVKITENRSK KTSFFRC
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分子量
26 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RAB8B is a member of the RAB family of small GTPases, which are crucial regulators of intracellular membrane trafficking and signal transduction. Within the context of cellular biology, RAB8B has garnered attention for its role in the regulation of vesicle transport processes, particularly in the context of the late steps of the endosomal and exocytic pathways. Understanding the function of RAB8B is essential due to its involvement in various cellular functions, including cell proliferation, differentiation, and polarity, and its potential links to disease states such as cancer and neurodegeneration. Studies have shown that RAB8B is implicated in the proper localization of proteins to the plasma membrane and is vital for the secretion of multiple signaling molecules. The recombinant expression of RAB8B in vitro provides researchers with valuable tools to investigate its biochemical properties, interaction with effector proteins, and overall contribution to cellular Homeostasis. Furthermore, characterizing RAB8B through recombinant protein techniques aids in deciphering its mechanisms of action and exploring its potential as a therapeutic target in pathologies linked to dysfunctional cellular trafficking. Consequently, the study of RAB8B recombinant protein is not only important for elucidating the fundamental aspects of intracellular transport dynamics but also for identifying novel strategies for disease intervention.
