Analytical Data
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基因名
GYS2
- Application
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别名
GYS2；Glycogen [starch] synthase. liver
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P54840
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表达区间
1-703aa
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氨基酸序列
MLRGRSLSVT SLGGLPQWEV EELPVEELLL FEVAWEVTNK VGGIYTVIQT KAKTTADEWG ENYFLIGPYF EHNMKTQVEQ CEPVNDAVRR AVDAMNKHGC QVHFGRWLIE GSPYVVLFDI GYSAWNLDRW KGDLWEACSV GIPYHDREAN DMLIFGSLTA WFLKEVTDHA DGKYVVAQFH EWQAGIGLIL SRARKLPIAT IFTTHATLLG RYLCAANIDF YNHLDKFNID KEAGERQIYH RYCMERASVH CAHVFTTVSE ITAIEAEHML KRKPDVVTPN GLNVKKFSAV HEFQNLHAMY KARIQDFVRG HFYGHLDFDL EKTLFLFIAG RYEFSNKGAD IFLESLSRLN FLLRMHKSDI TVMVFFIMPA KTNNFNVETL KGQAVRKQLW DVAHSVKEKF GKKLYDALLR GEIPDLNDIL DRDDLTIMKR AIFSTQRQSL PPVTTHNMID DSTDPILSTI RRIGLFNNRT DRVKVILHPE FLSSTSPLLP MDYEEFVRGC HLGVFPSYYE PWGYTPAECT VMGIPSVTTN LSGFGCFMQE HVADPTAYGI YIVDRRFRSP DDSCNQLTKF LYGFCKQSRR QRIIQRNRTE RLSDLLDWRY LGRYYQHARH LTLSRAFPDK FHVELTSPPT TEGFKYPRPS SVPPSPSGSQ ASSPQSSDVE DEVEDERYDE EEEAERDRLN IKSPFSLSHV PHGKKKLHGE YKN
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分子量
80.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GYS2, or glycogen synthase 2, is a key enzyme involved in glycogen synthesis, primarily expressed in liver and skeletal muscles. Its regulation is crucial for maintaining glucose homeostasis and energy metabolism. Research into GYS2 has gained attention due to its potential implications in metabolic disorders, such as diabetes and obesity. Mutations or dysfunctions in GYS2 can lead to glycogen storage diseases, impacting overall health. The recombinant expression of GYS2 protein allows for detailed biochemical studies, facilitating the exploration of its structural properties, enzymatic activity, and regulatory mechanisms. By producing GYS2 in a laboratory setting, researchers aim to elucidate its role in glycogen metabolism and its interactions with other metabolic pathways. Additionally, understanding the function of GYS2 at a molecular level could inform the development of therapeutic strategies for metabolic diseases, making it a significant target in biomedical research. Through techniques such as X-ray crystallography and enzymatic assays, scientists are investigating the protein's binding sites and catalytic functions, which might reveal novel insights into glycogen synthesis regulation and potential pharmacological interventions. Overall, GYS2 research represents a vital intersection of biochemistry, genetics, and clinical science that could have profound implications for treating metabolic health issues.
