Analytical Data
-
Gene name
SMCP
- Application
-
Alternative Names
SMCP;MCS;MCSP;Sperm mitochondrial-associated cysteine-rich Protein
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P49901
-
Expression Region
1-116aa
-
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMCDQTKH SKCCPAKGNQ CCPPQQNQCC QSKGNQCCPP KQNQCCQPKG SQCCPPKHNH CCQPKPPCCI QARCCGLETK PEVSPLNMES EPNSPQTQDK GCQTQQQPHS PQNESRPSK
-
Molecular Weight
15 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SMCP, or Sperm Microtubule-Associated Protein, has garnered significant interest in the field of reproductive biology and cell motility due to its unique structure and function. This protein is crucial for sperm maturation and motility, influencing the interaction between microtubules and sperm flagella. Studies have shown that SMCP plays a pivotal role in the assembly and stabilization of the axoneme—a fundamental structural component of the flagellum—contributing to the efficient movement of sperm. Investigating the molecular mechanisms behind SMCP's function helps to uncover the intricacies of sperm biology and potential fertility issues. Additionally, mutations or dysregulation of SMCP may lead to male infertility, making it a target for potential therapeutic interventions. Research into SMCP not only enhances our understanding of male reproductive health but also offers insights into microtubule dynamics, which are essential in various cellular processes, extending its relevance beyond reproductive systems to broader biological contexts. This growing body of work highlights the need for in-depth studies that could elucidate the functional pathways of SMCP and its interactions within the intricately regulated environment of the sperm cell.
