Analytical Data
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基因名
DOCK10
- Application
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别名
DOCK10；KIAA0694；ZIZ3；Dedicator of cytokinesis Protein 10
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96BY6
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表达区间
全长
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氨基酸序列
full
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分子量
249 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DOCK10 is a member of the DOCK (Dedicator of Cytokinesis) family of proteins, which play crucial roles in cellular processes such as cytoskeletal remodeling, cell migration, and immune responses. Research on DOCK10 has gained attention due to its involvement in various biological functions and disease mechanisms. Notably, DOCK10 has been implicated in the regulation of Rac GTPases, which are essential for actin cytoskeleton dynamics. Abnormal expression or mutations in DOCK10 have been associated with several conditions, including developmental disorders and cancers. Understanding the structure and function of DOCK10 is vital for unraveling its role in these diseases and for exploring potential therapeutic targets. Recent advances in protein engineering and structural biology techniques have facilitated the production and characterization of recombinant DOCK10 proteins, enabling researchers to investigate their functional mechanisms and interactions with other cellular components. This research is anticipated to provide insights into the fundamental processes governing cell behavior and contribute to the development of novel strategies for treating related diseases.
