Analytical Data
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Gene name
OR51E1
- Application
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Alternative Names
OR51E1; GPR164; OR51E1P; OR52A3P; POGR; PSGR2; Olfactory receptor 51E1; D-GPCR; G-protein coupled receptor 164; Olfactory receptor 52A3; Prostate-overexpressed G protein-coupled receptor; Prostate-specific G protein-coupled receptor 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8TCB6
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Expression Region
1-317 aa
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AA Sequence
MVDPNGNESSATYFILIGLPGLEEAQFWLAFPLCSLYLIAVLGNLTIIYIVRTEHSLHEP MYIFLCMLSGIDILISTSSMPKMLAIFWFNSTTIQFDACLLQMFAIHSLSGMESTVLLAM AFDRYVAICHPLRHATVLTLPRVTKIGVAAVVRGAALMAPLPVFIKQLPFCRSNILSHSY CLHQDVMKLACDDIRVNVVYGLIVIISAIGLDSLLISFSYLLILKTVLGLTREAQAKAFG TCVSHVCAVFIFYVPFIGLSMVHRFSKRRDSPLPVILANIYLLVPPVLNPIVYGVKTKEI RQRILRLFHVATHASEP
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Molecular Weight
35.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
OR51E1, a member of the olfactory receptor (OR) gene family, has garnered significant interest in recent years due to its atypical expression patterns and potential roles beyond traditional olfactory processes. While olfactory receptors are primarily known for their function in odorant detection in the nasal epithelium, OR51E1 has been implicated in various physiological responses and pathophysiological conditions, including cancer progression and metastasis. Studies have shown that OR51E1 is expressed in several non-olfactory tissues, suggesting it may play roles in cellular signaling pathways, impacting processes such as cell proliferation, migration, and apoptosis. The emergence of OR51E1 as a potential therapeutic target has prompted research into its signaling mechanisms, ligand specificity, and functional implications in different biological contexts. These investigations are critical for understanding how OR51E1 contributes to disease states, particularly in cancers where it may influence tumor microenvironments and patient outcomes. The recombinant protein of OR51E1 serves as a vital tool for these studies, enabling detailed examination of its structure-function relationships, interaction with other cellular receptors, and downstream signaling pathways. Investigating OR51E1 not only enriches the understanding of olfactory receptors but also broadens the scope of their biological significance, paving the way for novel therapeutic strategies in cancer and beyond.
