Analytical Data
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基因名
OR51E1
- Application
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别名
OR51E1; GPR164; OR51E1P; OR52A3P; POGR; PSGR2; Olfactory receptor 51E1; D-GPCR; G-protein coupled receptor 164; Olfactory receptor 52A3; Prostate-overexpressed G protein-coupled receptor; Prostate-specific G protein-coupled receptor 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8TCB6
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表达区间
1-317 aa
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氨基酸序列
MVDPNGNESSATYFILIGLPGLEEAQFWLAFPLCSLYLIAVLGNLTIIYIVRTEHSLHEP MYIFLCMLSGIDILISTSSMPKMLAIFWFNSTTIQFDACLLQMFAIHSLSGMESTVLLAM AFDRYVAICHPLRHATVLTLPRVTKIGVAAVVRGAALMAPLPVFIKQLPFCRSNILSHSY CLHQDVMKLACDDIRVNVVYGLIVIISAIGLDSLLISFSYLLILKTVLGLTREAQAKAFG TCVSHVCAVFIFYVPFIGLSMVHRFSKRRDSPLPVILANIYLLVPPVLNPIVYGVKTKEI RQRILRLFHVATHASEP
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分子量
35.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
OR51E1, a member of the olfactory receptor (OR) gene family, has garnered significant interest in recent years due to its atypical expression patterns and potential roles beyond traditional olfactory processes. While olfactory receptors are primarily known for their function in odorant detection in the nasal epithelium, OR51E1 has been implicated in various physiological responses and pathophysiological conditions, including cancer progression and metastasis. Studies have shown that OR51E1 is expressed in several non-olfactory tissues, suggesting it may play roles in cellular signaling pathways, impacting processes such as cell proliferation, migration, and apoptosis. The emergence of OR51E1 as a potential therapeutic target has prompted research into its signaling mechanisms, ligand specificity, and functional implications in different biological contexts. These investigations are critical for understanding how OR51E1 contributes to disease states, particularly in cancers where it may influence tumor microenvironments and patient outcomes. The recombinant protein of OR51E1 serves as a vital tool for these studies, enabling detailed examination of its structure-function relationships, interaction with other cellular receptors, and downstream signaling pathways. Investigating OR51E1 not only enriches the understanding of olfactory receptors but also broadens the scope of their biological significance, paving the way for novel therapeutic strategies in cancer and beyond.
