Analytical Data
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Gene name
GPR44
- Application
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Alternative Names
GPR44；CRTH2；DL1R；GPR44；Prostaglandin D2 receptor 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y5Y4
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Expression Region
1-395aa
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AA Sequence
MSANATLKPLCPILEQMSRLQSHSNTSIRYIDHAAVLLHGLASLLGLVENGVILFVVGCRMRQTVVTTWVLHLALSDLLASASLPFFTYFLAVGHSWELGTTFCKLHSSIFFLNMFASGFLLSAISLDRCLQVVRPVWAQNHRTVAAAHKVCLVLWALAVLNTVPYFVFRDTISRLDGRIMCYYNVLLLNPGPDRDATCNSRQVALAVSKFLLAFLVPLAIIASSHAAVSLRLQHRGRRRPGRFVRLVAAVVAAFALCWGPYHVFSLLEARAHANPGLRPLVWRGLPFVTSLAFFNSVANPVLYVLTCPDMLRKLRRSLRTVLESVLVDDSELGGAGSSRRRRTSSTARSASPLALCSRPEEPRGPARLLGWLLGSCAASPQTGPLNRALSSTSS
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Molecular Weight
43.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GPR44, also known as the chemokine receptor CXCR3, plays a crucial role in immune response and inflammation regulation by mediating the migration of immune cells. The receptor has garnered significant interest in research due to its involvement in various pathological conditions, including autoimmune diseases, cancer, and infectious diseases. Understanding the structure and function of GPR44 through the use of recombinant proteins enables researchers to elucidate the mechanisms underlying its signaling pathways and to identify potential therapeutic targets. Advances in recombinant DNA technology have facilitated the production of GPR44 in suitable expression systems, allowing for in-depth analyses, including functional assays and structural studies. These investigations are essential for developing drugs that can modulate GPR44 activity, providing novel strategies for treating diseases associated with dysregulated immune responses. The ongoing research on GPR44 recombinant proteins aims to enhance our understanding of its biological functions, paving the way for innovative therapeutic approaches to tackle diseases driven by inflammation and immune dysfunction.
