Analytical Data
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基因名
TPM3
- Application
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别名
TPM3；Tropomyosin alpha-3 chain
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P06753
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表达区间
2-285aa
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氨基酸序列
MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI
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分子量
59.8kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TPM3, or Tropomyosin 3, is a member of the tropomyosin protein family, which plays a crucial role in various cellular processes including muscle contraction, cell shape maintenance, and intracellular transport. Research into TPM3 has gained significant interest due to its involvement in cancer biology and its association with certain genetic disorders. Notably, mutations in the TPM3 gene have been linked to congenital myopathies and other neuromuscular diseases, highlighting its importance in muscle function and development. Additionally, the expression of TPM3 is regulated in a tissue-specific manner, suggesting its potential role as a biomarker for certain cancers. The study of recombinant TPM3 protein has become pivotal in elucidating its biochemical properties, interaction with other cytoskeletal components, and the mechanisms by which it influences cellular dynamics. By characterizing the recombinant form of TPM3, researchers aim to better understand its functional roles and develop targeted therapies for conditions associated with its dysregulation. This research could pave the way for new diagnostic and therapeutic strategies in treating TPM3-related diseases and improving our understanding of its contribution to cellular physiology.
