Analytical Data
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Gene name
BMS1
- Application
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Alternative Names
BMS1; BMS1L; KIAA0187Ribosome biogenesis Protein BMS1 homolog; Ribosome assembly Protein BMS1 homolog
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q14692
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Expression Region
1-403aa
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AA Sequence
MGKVWKQQMYPQYATYYYPQYLQAKQSLVPAHPMAPPSPSTTSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQNPNKYIPNGRPWHREGEAGMTLTYDPTTAAIQNGFYPSPYSIATNRMITQTSITPYIASPVSAYQVQSPSWMQPQPYILQHPGAVLTPSMEHTMSLQPASMISPLAQQMSHLSLGSTGTYMPATSAMQGAYLPQYAHMQTTAVPVEEASGQQQVAVETSNDHSPYTFQPNK
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Molecular Weight
70.07 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
BMS1 is a vital protein involved in ribosome biogenesis, particularly in the processing and maturation of ribosomal RNA (rRNA) and the assembly of ribosomal subunits. Research into BMS1 has gained importance due to its role in cellular growth and proliferation, as well as its implications in various diseases, including cancer and ribosomopathies—disorders caused by defects in ribosome production. BMS1 is known to interact with multiple nucleolar proteins, contributing to the dynamic processes of rRNA transcription and ribosome assembly. Its expression is tightly regulated, and alterations can lead to impaired ribosome function, impacting protein synthesis and cellular homeostasis. Understanding the structure and function of BMS1, especially when reconstituted in vitro, could provide insights into its mechanistic role and potential therapeutic targets. Overall, the study of BMS1 recombinant proteins enhances our knowledge of ribosome biology and its intricate networks, offering avenues for biomedical research and potential interventions in related diseases.











