Analytical Data
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基因名
PLEKHO1
- Application
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别名
C-Jun-binding protein; Casein kinase 2-interacting protein 1; CK2 interacting protein 1; CK2 interacting protein 1 HQ0024c protein; CK2-interacting protein 1; CKIP 1; CKIP-1; CKIP1; JBP; OC120; Osteoclast maturation associated gene 120 protein; Osteoclast maturation-associated gene 120 protein; PH domain-containing family O member 1; PKHO1_HUMAN; Pleckstrin homology domain containing family O member 1; Pleckstrin homology domain-containing family O member 1; PLEKHO1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q53GL0
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表达区间
1-409 aa
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氨基酸序列
MMKKNNSAKR GPQDGNQQPA PPEKVGWVRK FCGKGIFREI WKNRYVVLKG DQLYISEKEV KDEKNIQEVF DLSDYEKCEE LRKSKSRSKK NHSKFTLAHS KQPGNTAPNL IFLAVSPEEK ESWINALNSA ITRAKNRILD EVTVEEDSYL AHPTRDRAKI QHSRRPPTRG HLMAVASTST SDGMLTLDLI QEEDPSPEEP TSCAESFRVD LDKSVAQLAG SRRRADSDRI QPSADRASSL SRPWEKTDKG ATYTPQAPKK LTPTEKGRCA SLEEILSQRD AASARTLQLR AEEPPTPALP NPGQLSRIQD LVARKLEETQ ELLAEVQGLG DGKRKAKDPP RSPPDSESEQ LLLETERLLG EASSNWSQAK RVLQEVRELR DLYRQMDLQT PDSHLRQTTP HSQYRKSLM
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分子量
46.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PLEKHO1, or Pleckstrin Homology Domain-containing Protein 1, is a member of the pleckstrin homology (PH) domain-containing proteins, which are involved in various cellular processes including membrane trafficking, signal transduction, and cytoskeletal organization. The protein has garnered interest due to its potential roles in regulating cell migration, proliferation, and differentiation. Recent studies suggest that PLEKHO1 may be involved in the development of certain diseases, including cancer, where its expression levels can influence tumor behavior and patient outcomes. Additionally, PLEKHO1 has been implicated in immune responses, further highlighting its significance in both physiological and pathological processes. Given these factors, the recombinant expression and characterization of PLEKHO1 provide valuable insights into its functional mechanisms and potential therapeutic applications. Understanding the structure and interactions of this protein can aid in the identification of novel drug targets and contribute to the development of innovative treatment strategies for diseases where PLEKHO1 is a critical player. Thus, research on the recombinant PLEKHO1 protein is crucial for elucidating its biological roles and establishing its relevance in health and disease.
