Analytical Data
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基因名
PTAFR
- Application
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别名
PTAFR; PAFR; Platelet-activating factor receptor; PAF-R; PAFr
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P25105
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氨基酸序列
MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLTMADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVTRPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKGSVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAVFIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
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分子量
37.62 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PTAFR (Platelet Activating Factor Receptor) is a G-protein coupled receptor that plays a critical role in various physiological processes, including inflammation, immune response, and platelet activation. Research into PTAFR has gained momentum due to its involvement in pathological conditions such as asthma, cardiovascular diseases, and cancer. The receptor is activated by platelet-activating factor (PAF), a potent phospholipid mediator that orchestrates several cellular responses. Understanding the structural and functional dynamics of PTAFR through the study of its recombinant proteins has the potential to reveal insights into its signaling mechanisms and interactions with various ligands. This knowledge may pave the way for the development of novel therapeutic agents targeting PTAFR in diseases where its dysregulation is implicated. Furthermore, recombinant PTAFR proteins can serve as valuable tools for screening potential modulators and elucidating the downstream signaling pathways, contributing to a broader understanding of its role in health and disease. Thus, the investigation of PTAFR recombinant proteins is not only essential for basic science but also for translational applications in drug discovery and development.
