Analytical Data
-
Gene name
RAD9B
- Application
-
Alternative Names
RAD9B; Cell cycle checkpoint control protein RAD9B; DNA repair exonuclease rad9 homolog B; hRAD9B
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q6WBX8
-
Expression Region
1-426 aa
-
AA Sequence
MLKCVMSGSQ VKVFGKAVQA LSRISDEFWL DPSKKGLALR CVNSSRSAYG CVLFSPVFFQ HYQWSALVKM SENELDTTLH LKCKLGMKSI LPIFRCLNSL ERNIEKCRIF TRSDKCKVVI QFFYRHGIKR THNICFQESQ PLQVIFDKNV CTNTLMIQPR LLADAIVLFT SSQEEVTLAV TPLNFCLKSS NEESMDLSNA VHSEMFVGSD EFDFFQIGMD TEITFCFKEL KGILTFSEAT HAPISIYFDF PGKPLALSID DMLVEANFIL ATLADEQSRA SSPQSLCLSQ KRKRSDLIEK KAGKNVTGQA LECISKKAAP RRLYPKETLT NISALENCGS PAMKRVDGDV SEVSESSVSN TEEVPGSLCL RKFSCMFFGA VSSDQQEHFN HPFDSLARAS DSEEDMNNVC CRKEFNGSDA KYFCII
-
Molecular Weight
47.8 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RAD9B, a member of the RAD9 family of proteins, plays a significant role in the DNA damage response and cell cycle regulation. Research into RAD9B has gained momentum due to its implication in maintaining genomic stability, which is critical for preventing cancer progression. As a component of the 9-1-1 complex, RAD9B functions in DNA repair pathways, particularly in response to double-strand breaks and other forms of DNA damage. Evidence suggests that dysregulation of RAD9B may contribute to the development of various tumors, making it a potential biomarker for cancer prognosis and a target for therapeutic intervention. Additionally, studies have explored its interactions with other proteins and its regulatory mechanisms, shedding light on the intricate networks involved in cellular responses to genomic insults. The growing understanding of RAD9B's role in cellular processes has opened new avenues for exploring its potential in cancer treatment strategies, emphasizing the importance of continued research into this protein and its pathways in the context of tumor biology.
