Analytical Data
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基因名
C21orf66
- Application
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别名
PAX3- and PAX7-binding Protein 1. GC-rich sequence DNA-binding factor 1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y5B6
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表达区间
1-398aa
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氨基酸序列
MFRKARRVNVRKRNDSEEEERERDEEQEPPPLLPPPGTGEEAGPGGGDRAPGGESLLGPGPSPPSALTPGLGAEAGGGFPGGAEPGNGLKPRKRPRENKEVPRASLLSFQDEEEENEEVFKVKKSSYSKKIVKLLKKEYKEDLEKSKIKTELNSSAESEQPLDKTGHVKDTNQEDGVIISEHGEDEMDMESEKEEEKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARELGDFTPHDNEPGKGRLVREDENDASDDEDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSDDDALVTGEQDEELSRWEQEQIRKGINIPQVQASQPAEVNMYYQNTYQTMPYGSSYGIPYSYTAYGSSDAKSQKTDNTVPFKTPSNEMTPVTIDLVKKQLKDR
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分子量
70.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
C21orf66, also known as Chromosome 21 Open Reading Frame 66, is a gene located on chromosome 21 and has garnered interest in the scientific community due to its potential role in cellular processes and disease mechanisms. Research indicates that C21orf66 may be involved in various physiological functions, including cell signaling, proliferation, and apoptosis, with implications for understanding conditions such as Down syndrome and other genetic disorders. The protein encoded by C21orf66 is still not fully characterized, making it a compelling subject for further investigation. Recent studies have aimed at the recombinant expression of C21orf66 to elucidate its structure and function, employing techniques such as molecular cloning and protein purification. By studying the recombinant C21orf66 protein, researchers hope to uncover its biological activities, interactions with other cellular proteins, and its overall impact on cellular homeostasis. Such insights could pave the way for novel therapeutic strategies targeting C21orf66-related pathways in disease contexts. Additionally, the recombinant protein can serve as a valuable tool for developing diagnostic assays or experimental models, contributing to a deeper understanding of the implications of chromosome 21 anomalies in human health. Overall, the investigation of C21orf66 serves as a critical endeavor in elucidating the complex genetic landscape associated with chromosome 21 and its links to various pathologies.
