Analytical Data
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基因名
CCDC91
- Application
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别名
CCD91_HUMAN; CCDC91; Coiled coil domain containing 91; Coiled-coil domain-containing Protein 91; GGA binding partner; GGA-binding partner; GGABP; HSD8; p56 accessory Protein; p56
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q7Z6B0
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表达区间
1-441aa
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氨基酸序列
MPMWNKVSGVHLSPSSPEIVLDRDHSSSIGCLSSDAIISSPENTHAANSIVSQTIPKAQIQQSTHTHLDISLFPLGLTDEKSNGTIALVDDSEDPGANVSNIQLQQKISSLEIKLKVSEEEKQRIKQDVESLMEKHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQELEDMRKAGHEALSIIVDEYKALLQSSVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQRLLEMLDTEKELLKEKIKEALIQQSQEQKEILEKCLEEERQRNKEALVSAAKLEKEAMKDAVLKVVEEERKNLEKAHAEERELWKTEHAKDQEKVSQEIQKAIQEQRKISQETVKAAIIEEQKRSEKAVEEAVKRTRDELIEYIKEQKRLDQVIRQRSLSSLELFLSCAQKQLSALIATEPVDIE
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分子量
73.5 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCDC91 (Coiled-Coil Domain Containing 91) is a protein that has gained attention in cellular and molecular biology due to its potential roles in cilia formation and intracellular transport. Despite being identified as a coiled-coil domain protein, the specific biological functions and mechanisms of CCDC91 remain poorly understood. Recent studies suggest that CCDC91 may be involved in the assembly and maintenance of the centrosome and ciliary structures, which are crucial for various cellular processes, including signal transduction, cell division, and tissue homeostasis. Moreover, disturbances in ciliary function are linked to a range of human diseases, particularly ciliopathies, which emphasize the importance of understanding CCDC91's role in these pathologies. Efforts to produce recombinant CCDC91 protein enable researchers to investigate its structure and interactions with other proteins, further elucidating its functional contributions to cellular machinery. Given the increasing interest in the molecular pathways associated with cilia and centrosomes, CCDC91 represents a promising target for research aimed at uncovering new therapeutic approaches for related disorders.
