Analytical Data
-
Gene name
ABCC11
- Application
-
Alternative Names
ABCC11；MRP8；ATP-binding cassette sub-family C member 11
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q96J66
-
Expression Region
全长
-
AA Sequence
full
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ABCC11 is a member of the ATP-binding cassette (ABC) transporter family, which plays a crucial role in the transport of various molecules across cellular membranes. This protein is primarily involved in the secretion of metabolites and has garnered interest due to its significant implications in human health and disease. Notably, ABCC11 is associated with the regulation of earwax consistency, with specific genetic variants influencing whether individuals produce wet or dry earwax. Research has revealed that the presence or absence of this transporter affects not only earwax types but also influences axillary odor through the regulation of certain sweat components. Moreover, ABCC11 has been implicated in drug metabolism and resistance, particularly in cancer therapy. This has positioned it as a potential biomarker for therapeutic outcomes and as a target for drug development. Given its multifaceted roles, the recombinant production of ABCC11 protein in laboratory settings has become a key area of focus to facilitate further studies. By expressing and purifying ABCC11, researchers aim to elucidate its structural and functional properties, enabling a better understanding of its mechanisms and interactions within the human body. This information is crucial for exploring the potential of ABCC11 in precision medicine, particularly in tailoring treatments based on individual genetic backgrounds. Overall, the study of ABCC11 recombinant protein holds promise for advancing our knowledge of its diverse biological functions and its relevance in clinical applications.
