Analytical Data
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基因名
SNX10
- Application
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别名
2410004M09Rik; MGC109202; MGC33054; OPTB8; SNX10; SNX10_HUMAN; Sorting nexin 10; Sorting nexin-10
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y5X0
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表达区间
1-201 aa
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氨基酸序列
MFPEQQKEEF VSVWVRDPRI QKEDFWHSYI DYEICIHTNS MCFTMKTSCV RRRYREFVWL RQRLQSNALL VQLPELPSKN LFFNMNNRQH VDQRRQGLED FLRKVLQNAL LLSDSSLHLF LQSHLNSEDI EACVSGQTKY SVEEAIHKFA LMNRRFPEED EEGKKENDID YDSESSSSGL GHSSDDSSSH GCKVNTAPQE S
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分子量
23.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SNX10 (Sorting Nexin 10) is a member of the sorting nexin family, which plays a crucial role in intracellular trafficking and membrane dynamics. This protein is known to be involved in the endosomal-lysosomal pathway, where it assists in the sorting and transport of various cargo proteins. Recent studies have linked SNX10 to important cellular processes, including the regulation of phagocytosis, endosomal sorting, and autophagy, highlighting its significance in maintaining cellular homeostasis. Mutations in the SNX10 gene have been associated with various pathological conditions, including immunodeficiency disorders and cancer, thereby underscoring the protein's potential as a therapeutic target. The reconstitution of SNX10 in a laboratory setting allows for detailed structural and functional studies, aiding in the understanding of its role in cellular mechanisms and disease states. Furthermore, by investigating the protein’s interactions with other cellular components, researchers aim to elucidate the complex networks involved in membrane trafficking, providing insights into potential interventions in diseases related to SNX10 dysfunction. The generation of recombinant SNX10 protein is therefore crucial for advancing our understanding of its biological functions and therapeutic implications.
