Analytical Data
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基因名
TBRG4
- Application
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别名
Cell cycle progression protein 2; Cell cycle progression restoration protein 2; CPR2; FAST kinase domain containing protein 4 ; FAST kinase domain-containing protein 4; FASTKD4; KIAA0948; Protein TBRG4; Tbrg4; TBRG4_HUMAN; Transforming growth factor beta regulator 4
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q969Z0
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表达区间
1-631 aa
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氨基酸序列
MAAHLVKRCT CLLREAARQA PAMAPVGRLR LAWVAHKTLT SSATSPISHL PGSLMEPVEK ERASTPYIEK QVDHLIKKAT RPEELLELLG GSHDLDSNQA AMVLIRLSHL LSEKPEDKGL LIQDAHFHQL LCLLNSQIAS VWHGTLSKLL GSLYALGIPK ASKELQSVEQ EVRWRMRKLK YKHLAFLAES CATLSQEQHS QELLAELLTH LERRWTEIED SHTLVTVMMK VGHLSEPLMN RLEDKCLELV EHFGPNELRK VLVMLAAQSR RSVPLLRAIS YHLVQKPFSL TKDVLLDVAY AYGKLSFHQT QVSQRLATDL LSLMPSLTSG EVAHCAKSFA LLKWLSLPLF EAFAQHVLNR AQDITLPHLC SVLLAFARLN FHPDQEDQFF SLVHEKLGSE LPGLEPALQV DLVWALCVLQ QAREAELQAV LHPEFHIQFL GGKSQKDQNT FQKLLHINAT ALLEYPEYSG PLLPASAVAP GPSALDRKVT PLQKELQETL KGLLGSADKG SLEVATQYGW VLDAEVLLDS DGEFLPVRDF VAPHLAQPTG SQSPPPGSKR LAFLRWEFPN FNSRSKDLLG RFVLARRHIV AAGFLIVDVP FYEWLELKSE WQKGAYLKDK MRKAVAEELA K
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分子量
70.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TBRG4, a member of the TGF-beta receptor superfamily, has garnered attention for its potential roles in various biological processes, including cellular proliferation, differentiation, and apoptosis. Originally identified as a protein involved in the regulation of gene expression, TBRG4 has been shown to play crucial roles in developmental pathways and tissue homeostasis. Its involvement in various cancers raises the importance of understanding its function and regulatory mechanisms. Research indicates that TBRG4 may influence tumorigenesis and metastasis, making it a potential biomarker and therapeutic target. Many studies have explored the structural characteristics of TBRG4, revealing its unique domains and interaction partners, which contribute to its diverse functions in cellular signaling pathways. Additionally, the recombinant expression of TBRG4 allows for in-depth studies regarding its biochemical properties and interactions, helping to elucidate its role in both normal physiology and disease states. Understanding TBRG4's function could provide valuable insights into novel therapeutic strategies for cancer and other diseases related to TBRG4 dysregulation. The ongoing investigation into TBRG4's molecular mechanisms underscores its significance in biomedical research, paving the way for innovative treatments and diagnostic tools that target pathways influenced by this protein. Overall, the comprehensive study of TBRG4 recombinant protein not only enhances our understanding of its biology but also holds promise for advancing clinical applications in oncology and regenerative medicine.
