Analytical Data
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Gene name
EMD
- Application
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Alternative Names
EMD; EDMD; STA; Emerin
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P50402
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Expression Region
1-254aa
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AA Sequence
MDNYADLSDTELTTLLRRYNIPHGPVVGSTRRLYEKKIFEYETQRRRLSPPSSSAASSYSFSDLNSTRGDADMYDLPKKEDALLYQSKGYNDDYYEESYFTTRTYGEPESAGPSRAVRQSVTSFPDADAFHHQVHDDDLLSSSEEECKDRERPMYGRDSAYQSITHYRPVSASRSSLDLSYYPTSSSTSFMSSSSSSSSWLTRRAIRPENRAPGAGLGQDRQVPLWGQLLLFLVFVIVLFFIYHFMQAEEGNPF
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Molecular Weight
28.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
EML1 (Echinoderm microtubule-associated protein-like 1) is a member of the EML family of proteins, which are known to play critical roles in microtubule dynamics and cellular processes, including mitosis and cell signaling. Recent studies have highlighted the importance of EML1 in various biological contexts, such as neuronal development and the formation of cytoskeletal structures. Dysregulation of EML1 has been implicated in several diseases, including cancers and neurodevelopmental disorders. The recombinant expression of EML1 protein allows for the detailed study of its structural and functional properties, enabling researchers to explore its interactions with microtubules and associated proteins. This research is of significant interest because understanding the mechanism of EML1 can provide insights into its role in cellular organization and potential therapeutic targets for diseases linked to its dysfunction. Furthermore, the availability of EML1 in a recombinant form facilitates biochemical assays and structural analyses, paving the way for advanced therapeutic strategies that could manipulate EML1 function in pathological conditions. Overall, the investigation of EML1 recombinant protein represents a crucial step in unraveling the complexities of its biological functions and its implications in health and disease.
