Analytical Data
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基因名
ZNF17
- Application
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别名
ZNF17; KIAA1947; KOX10Zinc finger Protein 17; Zinc finger Protein HPF3; Zinc finger Protein KOX10
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P17021
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表达区间
1-662 aa
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氨基酸序列
MNLTEDYMVF EDVAIHFSQE EWGILNDVQR HLHSDVMLEN FALLSSVGCW HGAKDEEAPS KQCVSVGVSQ VTTLKPALST QKAQPCETCS SLLKDILHLA EHDGTHPKRT AKLYLHQKEH LREKLTRSDE GRPSFVNDSV HLAKRNLTCM QGGKDFTGDS DLQQQALHSG WKPHRDTHGV EAFQSGQNNY SCTQCGKDFC HQHTLFEHQK IHTEERPYEC SECGKLFRYN SDLIKHQRNH TGERPYKCSE CGKAFSLKYN VVQHQKIHTG ERPYECSECG KAFLRKSHLL QHQRIHTRPR PYVCSECGKA FLTQAHLVGH QKIHTGERPY GCNECGKYFM YSSALIRHQK VHTGERPFYC CECGKFFMDS CTLIIHQRVH TGEKPYECNE CGKFFRYRST LIRHQKVHTG EKPYECSECG KFFMDTSTLI IHQRVHTGEK PYECNKCGKF FRYCFTLNRH QRVHSGERPY ECSECGKFFV DSCTLKSHQR VHTGERPFEC SICGKSFRCR STLDTHQRIH TGERPYECSE CGKFFRHNSN HIRHRRNHFG ERSFECTECG RVFSQNSHLI RHQKVHTRER TYKCSKCGKF FMDSSTLISH ERVHTGEKPY ECSECGKVFR YNSSLIKHRR IHTGERPYQC SECGRVFNQN SHLIQHQKVH TR
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分子量
77.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZNF17, a member of the zinc finger protein family, is increasingly recognized for its potential roles in various biological processes, including gene regulation, cell differentiation, and oncogenesis. This protein is characterized by its zinc finger domains, which enable it to bind DNA and interact with other regulatory proteins, making it a pivotal player in transcriptional control. Research has shown that ZNF17 expression is often dysregulated in several cancers, suggesting its involvement in tumorigenesis and progression. The production of recombinant ZNF17 proteins serves as a critical step in elucidating the functional mechanisms underlying its activity, as well as its interaction with other cellular components. By utilizing advanced techniques such as recombinant DNA technology, researchers can produce ZNF17 in sufficient quantities for detailed biochemical analysis, structural studies, and functional assays. Understanding the molecular pathways influenced by ZNF17 may offer insights into its role as a potential biomarker for cancer prognosis and as a therapeutic target in cancer treatment. Given the growing interest in the functional implications of ZNF17, ongoing studies aim to explore its regulatory networks, post-translational modifications, and interaction with other signaling pathways, which could unravel new strategies for cancer intervention and therapy.
